Identifying Pathogens in the Field With F-FAST

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SOCOM operator uses F-FAST in the dark during Arctic Edge 24 inside a permafrost tunnel near Fairbanks, Alaska (photo credit: Parker Martin).
SOCOM operator uses F-FAST in the dark during Arctic Edge 24 inside a permafrost tunnel near Fairbanks, Alaska (photo credit: Parker Martin).

October 8, 2024 | Originally published by U.S. Army on August 27, 2024

Aberdeen Proving Ground, MD – Future battlefields require an on-the-go approach to the identification of whatever biological threat our Warfighters may come across. One such approach – Far-Forward Advanced Sequencing Technology, or F-FAST – uses rapid DNA and RNA sequencing systems for biothreat identification in far-forward environments.

While these types of tests normally require a degree of scientific know-how, researchers at the U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC) are working to make F-FAST’s rapid testing methods quicker and simpler than ever to address all potential biothreats – including those that are emerging and genetically modified.

As opposed to the previous forms of assays (e.g., COVID-19 type tests), there is a need for DNA/RNA sequencing capability – the next frontier in pathogen identification – as the threat of modified pathogens can obfuscate traditional methods. According to CBC Research Biologist Dr. Cory Bernhards, with F-FAST’s technology to perform rapid sequencing in the field, reachback genome assembly can then be the catalyst to create countermeasures such as therapeutics or vaccines.

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