New DNA Biosensor Could Unlock Powerful, Low-Cost Clinical Diagnostics

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In a new study, researchers demonstrate the capability of DNA biosensor components for a unique modular DNA biosensor. The researchers plan to integrate their design within a device the size and shape of a smartphone for low-cost clinical diagnostics (source: 
 NIST).
In a new study, researchers demonstrate the capability of DNA biosensor components for a unique modular DNA biosensor. The researchers plan to integrate their design within a device the size and shape of a smartphone for low-cost clinical diagnostics (source: NIST).

January 31, 2023 | Originally published by National Institute of Standards and Technology on January 24, 2023

DNA can signal the presence of or predisposition to a slew of diseases, including cancer. The ability to flag down these clues, known as biomarkers, allows medical professionals to make critical early diagnoses and provide personalized treatments. The typical methods of screening can be laborious, expensive, or limited in what they can uncover. A new biosensor chip that boasts an accurate and inexpensive design may increase accessibility to high-quality diagnostics.

The biosensor, developed by researchers at the National Institute of Standards and Technology (NIST), Brown University, and the French government-funded research institute CEA-Leti, identifies biomarkers by measuring how binding occurs between DNA strands and the device. What sets it apart from other similar sensors is its modular design, which lowers costs by making it easier to mass produce and allowing the most expensive components to be reused.

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